Chronic liver failure, also called end-stage liver disease, occurs when your liver is so damaged that it can no longer perform important tasks, such as removing toxins from your body. The causes of end-stage liver disease vary but may include:
- Alcohol-associated liver disease
- Alpha-1 antitrypsin deficiency
- Autoimmune hepatitis
- Biliary atresia
- Hemochromatosis
- Hepatitis B
- Hepatitis C
- Nonalcoholic fatty liver disease
- Primary biliary cirrhosis
- Sclerosing cholangitis
- Wilson’s disease
Liver cancer known as hepatocellular carcinoma or certain types of primary bile duct cancer called cholangiocarcinoma may also be reasons for liver transplantation.