My Locations
About Me
I am a colorectal surgeon and researcher who has been at Duke for about 25 years. I see patients who have issues with the small bowel, colon, rectum and anus. These issues include benign tumors, cancers, hemorrhoids and fistulas. The best part of my job is operating. The operating room is a special place, where we have been able to put a number of processes in place so things run smoothly and we can give patients the best chance at a good outcome. The fact that you can take a condition, operate and potentially cure a patient is fascinating to me. As a faculty member, I also enjoy when I have the chance to teach residents during the operation. When I am not at work, I enjoy fishing, hiking and playing tennis with my children.
- Professor of Surgery, Surgical Oncology 2015
- Vice Chair of Clinical Operations, Surgery 2023
- Member of the Duke Cancer Institute, Duke Cancer Institute 1999
Call for an Appointment
Areas of Expertise
- Anorectal Disease
- Colorectal Cancer
- Diverticulitis
- Inflammatory Bowel Disease
Ratings and Reviews
The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
In the News
Loading
Loading
Clinical Focus and Research
My research interests include surgical outcomes and quality. I am deeply committed to understanding how physicians can make our clinical outcomes better. I am the departmental leader in quality and the surgical champion for the National Quality Improvement Projects. In addition, I am interested in all aspects of research into colorectal cancer, including basic science and examining large databases to compare techniques and optimize cancer survival.
-
Intraoperative Ureter Visualization using ASP5354 with NIR-F Imaging (Abdominal and Pelvic Surgery)IRB# PRO00116263 , NCT# NCT05754333
- A Phase 3, Multicenter, Prospective, Randomized, Open-label Study for Intraoperative Ureter(s) Visualization When Using ASP5354 with Near-infrared Fluorescence (NIR-F) Imaging in Adult Participants Undergoing Minimally Invasive and Open Abdominopelvi awarded by Astellas Pharma Global Development, Inc 2024 - 2029
- Inhibition of CaMKK2 sensitizes rectal cancers to radiation therapy awarded by National Institutes of Health 2021 - 2022
- Fuente, Sebastian G. de la, L Scott Levin, James D. Reynolds, Carmen Olivares, Theodore N. Pappas, Kirk A. Ludwig, and Christopher R. Mantyh. “Elective stoma construction improves outcomes in medically intractable pressure ulcers.” Dis Colon Rectum 46, no. 11 (November 2003): 1525–30. https://doi.org/10.1007/s10350-004-6808-6.
- Kihara, N., S. G. de la Fuente, K. Fujino, T. Takahashi, T. N. Pappas, and C. R. Mantyh. “Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats.” Gut 52, no. 5 (May 2003): 713–19. https://doi.org/10.1136/gut.52.5.713.
- Kalady, Matthew F., Ryan C. Fields, Stephen Klein, Karen C. Nielsen, Christopher R. Mantyh, and Kirk A. Ludwig. “Loop ileostomy closure at an ambulatory surgery facility: a safe and cost-effective alternative to routine hospitalization.” Dis Colon Rectum 46, no. 4 (April 2003): 486–90. https://doi.org/10.1007/s10350-004-6587-0.
- Moore, H. G., and C. R. Mantyh. “Technique of ileostomy construction and closure.” In Fischer’s Mastery of Surgery, Seventh Edition, 2:1638–49, 2018.
- Sun, Z., M. A. Adam, and C. R. Mantyh. “Colonic arteriovenous malformations.” In Gastrointestinal Bleeding: A Practical Approach to Diagnosis and Management, Second Edition, 159–67, 2016. https://doi.org/10.1007/978-3-319-40646-6_14.
- Olcese, V. A., and C. R. Mantyh. “Bleeding colonic tumors.” In Gastrointestinal Bleeding: A Practical Approach to Diagnosis and Management, 163–71, 2010. https://doi.org/10.1007/978-1-4419-1693-8_15.
- Liu, Annie, Melissa Lowe, Donna Niedzwiecki, Kristen E. Rhodin, Jeremy Sharib, Benjamin Wildman-Tobriner, Terence Z. Wong, et al. “Perioperative and Oncologic Outcomes of Hepatic Arterial Infusion (HAI) Pump Chemotherapy for Patients with Unresectable Colorectal Liver Metastases at an Expanding HAI Program.” In Ann Surg Oncol, 32:1033–42, 2025. https://doi.org/10.1245/s10434-024-16488-y.
- Masoud, Sabran J., Alex J. Bartholomew, Michael Lidsky, Allison N. Martin, Daniel Nrussbaum, Dan G. I. I. I. Blazer, Leila Mureebe, Christopher R. Mantyh, and Peter J. Allen. “Social Vulnerability as a Neighborhood-level Determinant of Pancreatic Cancer Surviviorship: A National Analysis of Veterans Affairs Patients.” In ANNALS OF SURGICAL ONCOLOGY, 31:S160–S160, 2024.
- Hayden, Joshua P., William R. Boysen, Urszula Kowalik, Brian M. Inouye, John Migaly, Christopher R. Mantyh, Detlev Erdmann, and Andrew C. Peterson. “Outcomes of an Algorithmic, Multidisciplinary Approach to Rectourethral Fistula Repair: A Pre- and Postintervention Quasi-Experimental Study.” In Dis Colon Rectum, 66:598–608, 2023. https://doi.org/10.1097/DCR.0000000000002467.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
-
Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
-
Ambetter
- Ambetter of North Carolina
-
Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
-
*Duke HomeCare and Hospice does not participate in the plan.
-
Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
-
*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
-
Duke Group Plans
- Duke Basic
- Duke Select
-
Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
-
Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
-
Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
-
NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
-
TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
-
United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
-
*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
-
**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
- Becton, Dickinson and Company
- Vertex Pharmaceuticals Inc.