TAILOR-RT for Low-Risk Breast Cancer - Clinical Trial
What is the Purpose of this Study?
We are doing this study to find out if it is better to give patients with low-risk breast cancer regional radiation therapy as part of their standard treatment after surgery or if it is better to not give radiation. Regional radiotherapy is currently the standard treatment after surgery for low-risk breast cancer but we do not know if it is necessary in all cases.
Breast Cancer
Who Can Participate in the Study?
Women ages 35+ who:
- Are newly diagnosed with invasive carcinoma of the breast that has no evidence of metastases
- Have or will be treated with breast-conserving surgery or mastectomy with clear margins
For more information, contact the study team at emily.watson@duke.edu.
What is Involved?
If you choose to join this study, you will get a random assignment (like a coin flip) to 1 of 2 groups.
Group 1
If you are in this group, you will not get regional radiotherapy. Your study regimen will be as follows:
- If you have surgery to remove part of the breast (called breast conserving surgery), you will receive radiation aimed at the breast only (whole breast radiation); OR
- If you have surgery to remove the whole breast (called mastectomy), you will receive no radiation therapy
Group 2
If you are in this group, you will get regional radiotherapy after your surgery. Your study regimen will be as follows:
- If you have breast conserving surgery, you will get whole breast radiation and additional radiation aimed at the surrounding lymph nodes (regional radiation); OR
- If you have a mastectomy, you will receive regional radiation aimed at the chest area and the surrounding lymph nodes
Study Details
