Peripheral Nerve Injury

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Peripheral nerve injury is a type of neuropathy that causes pain, numbness, tingling, weakness, hypersensitivity, or paralysis. Left untreated, it can significantly impact your daily life. Duke Health's peripheral neuropathy specialists use the latest advances to diagnose your condition, and, when appropriate, a full spectrum of surgical techniques to treat it. We help you manage your neuropathy, so you experience a better quality of life. 

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About Peripheral Nerve Injury

Peripheral nerve injuries and nerve damage disrupt the flow of messages between your brain and your body. They can occur in all nerves that arise outside the spinal cord. If you suspect you have a peripheral nerve injury, it’s important to see a specialist quickly to ensure a timely diagnosis and be considered for all treatment options. 

Peripheral neuropathy may be caused by: 

Nerve Compression
Nerve compression occurs when the nerve is under too much pressure from surrounding tissues. Carpal tunnel syndrome is nerve compression at the wrist. Nerve compression may occur elsewhere in the body, such as in the neck, chest, wrist, elbow, forearm, hip, leg, foot, and ankle.

Traumatic Nerve Injuries
Trauma caused by an accident or by playing sports may result in peripheral nerve injuries. The nerve may be torn, stretched, cut, or crushed. When this happens to nerves in the hand, arm, or shoulder, it's known as a brachial plexus injury. This may also occur at birth

Tumors Growing on the Nerve 
Noncancerous nerve tumors include schwannomas and neurofibromas. Malignant peripheral nerve sheath tumors are rare cancers that develop in the sheaths that surround peripheral nerves. 

Conditions and Injuries
Peripheral neuropathy may be caused by a condition you're born with, such as cerebral palsy, or an injury to the brain or spine, such as stroke, traumatic brain injury, or spinal cord injury

Auto-Immune Disease
Parsonage-Turner Syndrome is a rare disease that can affect nerves in the shoulder, arm, and hand.  

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Diagnosing Peripheral Nerve Injury

Duke specialists use advanced technology to diagnose your nerve injury and inform your treatment plan.

Imaging

Ultrasound, CT, and/or MRI scans can detect spine problems, enlarged nerves, inflammation, cuts in the nerve, and tumors that could cause symptoms.

Nerve Conduction Study (NCS)

Small, flat electrodes are taped to the skin over a muscle or nerve. Nerves are then stimulated with small electrical shocks from a probe placed against the skin. These results are analyzed to help identify nerve dysfunction.

Electromyogram (EMG) Test

A thin, sterile needle electrode is inserted through the skin into a muscle. The needle measures how much electrical activity is generated by the nerve and sent to the muscle. This helps figure out whether it’s the nerve or muscle that is malfunctioning.

Nerve Biopsy

A small piece of nerve is removed and examined under a microscope. This can help find the underlying cause of nerve pain.

Our Locations

Duke Health offers locations throughout the Triangle. Find one near you.

Treatment for Peripheral Nerve Injury

If physical and occupational therapy are not enough to treat your peripheral neuropathy, your doctor may recommend injections of a pain medication and a steroid that reduce the inflammation, or pain-relieving peripheral nerve stimulators that are  placed temporarily under the skin. 

If your symptoms persist, Duke neurosurgeons, orthopedic surgeons, and plastic surgeons offer a variety of surgical procedures to treat your peripheral nerve injury. 

Nerve Decompression

During nerve decompression, the surgeon removes tissue, bone, or other structures that are putting pressure on the nerve. 

Nerve Repair and Nerve Graft

During a nerve repair or nerve graft, the surgeon removes damaged nerve tissue and reconnects the healthy ends of the nerve end-to-end or with nerve conduits and graft depending on the injury.

Nerve Transfer Surgery

This procedure aims to restore feeling and mobility in the limbs by replacing damaged nerves with functioning nerves from another part of your body.

Tendon and Muscle Transfer

During tendon and muscle transfer, tendons are removed from their original insertion points and reattached to a different bone or tendon. This can improve function, and may be done alongside or following nerve surgery. 

Why Choose Duke

Deep Expertise in Treating Neuropathy
As a national referral center, our surgeons routinely address challenging cases. Our team of specialists work together to diagnose the cause of your pain and outline a treatment plan that incorporates the latest advances in non-surgical and surgical approaches.

Team Approach to Care
Duke’s team approach to care unites experts in neurology, physiatry, anesthesiology, orthopaedic surgery, neurosurgery, plastic surgery, pain management, mental health, and physical and occupational therapy to evaluate and treat you, ensuring a comprehensive approach to care for nerve injuries.

Active Research and Development Program
Duke’s researchers are working to understand and optimize the body’s response and interactions that occur following nerve injury and during nerve regeneration. They seek to use that understanding to develop medications and devices that enhance nerve regeneration and preserve muscle function.

Access to Clinical Trials
You may have access to the latest peripheral nerve injury treatment methods and technologies through clinical trials at Duke.

Best Hospital for Orthopaedics, Neurosurgery in NC

Where you receive your care matters. Duke University Hospital is proud of our team and the exceptional care they provide. They are why our orthopaedics, neurology, and neurosurgery programs are nationally ranked, and are the highest-ranked programs in North Carolina, according to U.S. News & World Report for 2024–2025.

This page was medically reviewed on 01/13/2025 by