Causes of Primary Immunodeficiency Disease
The immune system is the body’s defense system. It fights infections and keeps the body healthy and strong as well as regulates immune responses to prevent autoimmune disease. Primary immunodeficiency diseases are caused by genetic defects that impact how the immune system works. The lack of a normal, functioning immune system can lead to serious respiratory, digestive, and neurologic problems that can include organ damage and problems moving or functioning. Primary immunodeficiency diseases can also increase one’s risk for cancer and autoimmune diseases. Early and accurate diagnosis and treatment can make a difference in a child’s quality of life.
There more than 353 primary immunodeficiency diseases. Common types we treat include:
- Severe Combined Immunodeficiency Disease (SCID) -- often referred to as Bubble-Boy Syndrome
- DiGeorge Syndrome
- Agammaglobulinema (X-linked and Autosomal Recessive)
- Chronic Granulomatous Disease
- Common Variable Immune Deficiency