My Locations
Part of the Duke Cancer Institute
About Me
As an orthopedic oncologist, I treat cancers of the bone and muscle. My background is very different from most doctors. I started as a veterinarian and became interested in cancer because so many dogs have cancer, and I came to medical school to learn how to treat and beat some of these types of cancer. I’m still a veterinarian, and that’s a big part of what we do here. Many cancers of the bone and muscles, called sarcomas, are rare in people, but common in dogs. So continuing to treat dogs with this type of cancer lets us and our group gain a deeper understanding of how these cancers work. With my patients, I try to find out what the cancer has taken from them, and what their goals are for how to get back in control. For some, their goal is to beat the cancer no matter what. For others, the goal is to keep walking or to be able to walk again, or to be in less pain. Then we try to tailor our approach to the patient. Often, people think being a surgical oncologist must be a terrible job. But I find something in each patient to admire, because patients dealing with cancer develop a strength the rest of us don’t get to have.
- Frank H. Bassett III, M. D. Associate Professor of Orthopaedic Surgery, Orthopaedic Surgery 2022
- Associate Professor of Orthopaedic Surgery, Orthopaedic Surgery 2023
- Associate Professor of Pathology, Pathology 2022
Ratings and Reviews
The ratings and reviews are based on patient responses to the overall provider rating question from the survey. The question reads: “Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?” Responses are converted to a 5-point rating system and applied consistently to all providers. Learn more about our survey process. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
Clinical Focus and Research
My laboratory focuses on comparative oncology -- the study of cancers from one species to another. Because sarcomas are rare in people but common in dogs, we attempt to learn as much as we can from every patient with a sarcoma, regardless of whether that patient walks on two legs or four.
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X-PACT Immunolight (Breast Cancer, Head & Neck Cancer, Melanoma, and Sarcoma)IRB# PRO00105022 , NCT# NCT04389281
- Phase 1 Study of X-PACT (X-ray Psoralen Activated Cancer Therapy) awarded by Immunolight, LLC 2021 - 2026
- Zamora, Tomas, Eduardo Botello, Thomas Jenkins, Charlotte Jeys, Minna Laitinen, Ajay Puri, Lee Jeys, and BOOM consensus meeting participants. “Global and regional disparities in access to specialist sarcoma services.” Bone Jt Open 6, no. 4 (April 11, 2025): 425–31. https://doi.org/10.1302/2633-1462.64.BJO-2024-0208.R1.
- Hong, Alexander, Atharva Vispute, Serafina Turner, Rita Glazer, Zachary A. Weishampel, Ashley Huang, Zachary A. Holmes, et al. “An informatics-based analysis platform identifies diverse microbial species with plastic-degrading potential.” Sci Total Environ 973 (April 10, 2025): 179075. https://doi.org/10.1016/j.scitotenv.2025.179075.
- Zachem, Tanner J., Jacob E. Sperber, Sully F. Chen, Syed M. Adil, Benjamin D. Wissel, Gregory Chamberlin, Edwin Owolo, et al. “Intraoperative brain tumor classification via laser-induced fluorescence spectroscopy and machine learning.” J Neurosurg, April 4, 2025, 1–10. https://doi.org/10.3171/2024.12.JNS242041.
- Colmenares, V., W. C. Eward, and L. A. Graves. “From Evolutionary Biology to Bedside and Beyond: A View of Comparative Oncology throughout the Translational Pipeline.” In Cancer through the Lens of Evolution and Ecology, 170–84, 2024. https://doi.org/10.1201/9781003307921-13.
- Larrier, N., W. Eward, and R. F. Riedel. “Bone Sarcomas.” In Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors and Supportive Care, 1:567–78, 2023. https://doi.org/10.1002/9781119823766.ch43.
- Larrier, N., W. C. Eward, and R. F. Riedel. “Bone Sarcomas.” In Cancer Consult: Expertise for Clinical Practice, 687–95, 2014. https://doi.org/10.1002/9781118589199.ch105.
- Schleupner, Beatrice, Alexandra Hunter Aitchison, Elle MacAlpine, Nicole Cantor, Jason Somarelli, Brian Brigman, Julia Visgauss, Michael Monument, and William Eward. “Abstract 6642: Exploring the x-ray psoralen activated cancer therapy mechanism of action in a genetically engineered mouse model of soft tissue sarcoma.” In Cancer Research, 84:6642–6642. American Association for Cancer Research (AACR), 2024. https://doi.org/10.1158/1538-7445.am2024-6642.
- Nguyen, Valerie U., Laurie Graves, Veronica Colmenares, Abol Macabangon, Casey Syal, Kelsey Fisher-Wellman, William C. Eward, So Young Kim, and Jason A. Somarelli. “Abstract 1085: Exploiting bioenergetic vulnerabilities in chemotherapy resistant osteosarcoma.” In Cancer Research, 84:1085–1085. American Association for Cancer Research (AACR), 2024. https://doi.org/10.1158/1538-7445.am2024-1085.
- Foreman, Jordan, Kevin Krughoff, William Eward, Edward Hendershot, Christopher Mantyh, and Andrew Peterson. “SEVERE POST-OPERATIVE COMPLICATIONS ARE RARE IN PATIENTS WITH URINARY-PUBIC SYMPHYSIS FISTULAE AND PUBIC BONE OSTEOMYELITIS (UPF-OM) UNDERGOING EXTIRPATIVE SURGERY; DATA FROM THE NATIONAL SURGICAL QUALITY IMPROVEMENT PROGRAM.” In JOURNAL OF UROLOGY, 209:E467–E467, 2023.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.