Shruti M. Raja, MD
Neurologist
My Locations
About Me
I care for patients with neuromuscular disorders, which include muscular dystrophy, neuropathy, autoimmune muscle, and nerve conditions, as well as inherited ones. A lot of my work is focused on a holistic approach, so I don’t just focus on the treatment of the disease, but also the way the disease is affecting the rest of the patient’s life and quality of life. I will spend the majority of my visit talking with the patient, then do a full neurological exam, and then discuss potential options and potential diagnoses. If it is a condition that is autoimmune, we can discuss various therapies that can be used and other needs at home related to mobility or basic function. Our patients have a variety of different conditions that can cause problems with breathing, cardiac abnormalities, endocrine dysfunction, and mobility problems. Our clinic here at Duke is unique because we offer multiple consultants working as a team to give the best holistic care to a patient.
- Assistant Professor of Neurology, Neurology, Neuromuscular Disease 2021
- Faculty Director of Duke Early Phase Research Unit, Neurology 2022
- Co-Medical Director of Duke Clinical Research at Pickett Road, Neurology 2022
Call for an Appointment
Areas of Expertise
- Neuromuscular Disorders
- Myasthenia Gravis
- Lambert-Eaton Myasthenic Syndrome
Ratings and Reviews
The ratings and reviews are based on patient responses to the overall provider rating question from the survey. The question reads: “Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?” Responses are converted to a 5-point rating system and applied consistently to all providers. Learn more about our survey process. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
Clinical Focus and Research
My research emphasizes the development of new therapies and outcome measures for autoimmune neuromuscular conditions. This is a diverse group of conditions that includes disorders of neuromuscular transmission such as myasthenia gravis, Lambert Eaton Myasthenia, and inflammatory disorders of muscle and nerves.
- A multicenter, randomized, prospective double-blind, cross-over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of the central nervous system (CNS), awarded by Bayer Healthcare Pharmaceuticals Inc 2024 - 2028
- Raja, Shruti M., Jeffrey T. Guptill, Michelle Mack, Marni Peterson, Stephen Byard, Robert Twieg, Lynn Jordan, et al. “A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)-Hydroxynorketamine in Healthy Volunteers.” Clin Pharmacol Ther 116, no. 5 (November 2024): 1314–24. https://doi.org/10.1002/cpt.3391.
- Raja, Shruti M. “Steroid Use and Perioperative Complications of Thymectomy in Myasthenia Gravis.” Ann Thorac Surg 115, no. 6 (June 2023): 1558–59. https://doi.org/10.1016/j.athoracsur.2022.11.032.
- Lodise, Thomas P., J Nicholas O’Donnell, Shruti Raja, Jeffrey T. Guptill, Smitha Zaharoff, Nyssa Schwager, Vance G. Fowler, et al. “Safety of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase I, Open-Label Study in Healthy Adult Volunteers.” Antimicrob Agents Chemother 66, no. 12 (December 20, 2022): e0093522. https://doi.org/10.1128/aac.00935-22.
- Harada, Yohei, Margaret Bettin, Vern C. Juel, Lisa D. Hobson-Webb, Shruti M. Raja, Donald B. Sanders, and Janice M. Massey. “Pregnancy in MuSK-positive myasthenia gravis: A single-center case series.” In Muscle Nerve, 68:85–90, 2023. https://doi.org/10.1002/mus.27839.
- Sanders, Donald B., Michael W. Lutz, Shruti M. Raja, Vern C. Juel, Jeffrey T. Guptill, Lisa D. Hobson-Webb, and Janice M. Massey. “The Duke Myasthenia Gravis Clinic Registry: II. Analysis of outcomes.” In Muscle Nerve, 67:291–96, 2023. https://doi.org/10.1002/mus.27794.
- Gable, Karissa, John Yi, Melissa Russo, Doug Emmett, Natalia Gonzalez, Shruti Raja, Yingkai Li, and Jeffrey Guptill. “Enhanced CD4 and CD8 T cell responses in Chronic Inflammatory Demyelinating Polyneuropathy.” In JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 26:405–405, 2021.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
- Ocaro Pharmaceuticals
- Ovid Therapeutics
- Regeneron Pharmaceuticals