Paul B. Rosenberg, MD
Advanced Heart Failure Specialist, Transplant Cardiologist
My Locations
About Me
I am a cardiologist with a specialty in heart failure and transplant cardiology. I became a cardiologist because I enjoy interacting with and helping patients with complicated cardiac problems that require all of my clinical skills. It is really rewarding to see very sick challenging patients realize greater mobility and improved quality of life after working with them over months or even years. Here at Duke, we believe that developing strong personal relationships with our patients is fundamental to their success. I try to take a personal approach with each patient to encourage them to engage in a healthy lifestyle and to optimize their medical regimens to best suit their problems. A collaborative team of clinicians, nurses and staff work to achieve the best for our patients.
- Professor of Medicine, Medicine, Cardiology 2024
- Associate Professor of Pathology, Pathology 2022
- Member of Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2013
Call for an Appointment
Areas of Expertise
- Heart Failure
- Heart Transplant Evaluation
- VAD Evaluation Care
- Cardiac Prevention
- Multi-Organ Transplant
Ratings and Reviews
The ratings and reviews are based on patient responses to the overall provider rating question from the survey. The question reads: “Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?” Responses are converted to a 5-point rating system and applied consistently to all providers. Learn more about our survey process. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
Clinical Focus and Research
My research program seeks to understand how changes in calcium are decoded by a cell in order to activate signaling pathways that control gene expression, proliferation, and metabolism. In particular, we are interested in Ca2+ entry pathways including store-operated Ca2+ entry (SOCE) and transient receptor potential channels(TRPC). We have demonstrated that stromal interaction molecule 1 (STIM1) activates SOCE in muscle in order to adapt muscle function for exercise. In addition, we are interested in the role of TRPC channels in cardiac myocyte, islet, and podocyte cell proliferation. Realization of our research objectives including the discovery of therapeutic targets will have important implications for many chronic diseases, particularly heart failure.
- STIM1 and mitochondrial quality control awarded by National Institutes of Health 2017 - 2024
- Duke Training Grant in Nephrology awarded by National Institutes of Health 1995 - 2023
- Fuchs, Michaela A. A., Emily J. Burke, Nejla Latic, Susan L. Murray, Hanjun Li, Matthew A. Sparks, Dennis Abraham, et al. “Fibroblast growth factor 23 and fibroblast growth factor receptor 4 promote cardiac metabolic remodeling in chronic kidney disease.” Kidney Int 107, no. 5 (May 2025): 852–68. https://doi.org/10.1016/j.kint.2025.01.024.
- Bryson, Victoria, Chaojian Wang, Zirui Zhou, Kavisha Singh, Noah Volin, Eda Yildirim, and Paul Rosenberg. “The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice.” J Clin Invest 134, no. 7 (February 1, 2024). https://doi.org/10.1172/JCI170317.
- Datta, Somenath, Brett M. Antonio, Nathan H. Zahler, Jonathan W. Theile, Doug Krafte, Hengtao Zhang, Paul B. Rosenberg, et al. “APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.” J Clin Invest 134, no. 5 (January 16, 2024). https://doi.org/10.1172/JCI172262.
- Stiber, J. A., and P. B. Rosenberg. “Skeletal muscle store-operated Ca2+ entry and STIM/Orai signaling in skeletal muscle.” In Store-Operated Ca2+ Entry (SOCE) Pathways: Emerging Signaling Concepts in Human (Patho)Physiology, 435–47, 2013. https://doi.org/10.1007/978-3-7091-0962-5_27.
- Zhang, Hengtao, Albert Y. Sun, Jong J. Kim, Victoria Graham, Elizabeth A. Finch, Igor Nepliouev, Guiling Zhao, et al. “STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.” In Proc Natl Acad Sci U S A, 112:E5618–27, 2015. https://doi.org/10.1073/pnas.1503847112.
- Stiber, Jonathan A., Lisheng Zhang, Igor Nepliouev, Zhu-Shan Zhang, Jiao-Hui Wu, Paul B. Rosenberg, and Neil J. Freedman. “The Actin-Binding Protein Drebrin Reduces TRP Channel Activity and Neointimal Hyperplasia.” In CIRCULATION, Vol. 126. LIPPINCOTT WILLIAMS & WILKINS, 2012.
- Smith, Alastair D., Meaghan L. McKinnon, Chetan B. Patel, Deepak Vikraman-Sushama, Gary M. Felker, Debra L. Sudan, Paul B. Rosenberg, Adrian F. Hernandez, Carmelo A. Milano, and Joseph G. Rogers. “Successful Organ Donation and Outcomes Following Long-Term Circulatory Support with Non-Pulsatile Mechanical Support.” In LIVER TRANSPLANTATION, 18:S244–S244. WILEY-BLACKWELL, 2012.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.