Eileen Tsai Chambers, MD
Pediatric Kidney Transplant Specialist, Pediatric Nephrologist
My Locations
About Me
I became a physician to improve the health and well-being of children. I was drawn to the field of pediatric kidney transplantation as it combined my love for immunology and central goal of enhancing patient outcomes. My ultimate goal is to provide individually tailored immune therapy and monitoring to enhance the lives of transplanted children.
- Associate Professor of Pediatrics, Pediatrics, Nephrology 2021
- Associate Professor in the Department of Surgery, Surgery, Abdominal Transplant Surgery 2020
Call for an Appointment
Areas of Expertise
- Kidney Disease in Children
- Pediatric Kidney Transplant Evaluation
- Pediatric Immune Disorders
- Neurogenic Bladder
- Nephrotic Syndrome and Focal Segmental Glomerulosclerosis
- Obstructive Uropathy
- Issues from Prior Transplant with High Antibody Titers
Training and Education
In the News
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Clinical Focus and Research
My interest in transplant immunology, combined with my desire to improve kidney transplant outcomes, led me to focus on B cell immune responses. I found a correlation with B cell markers and poor kidney transplant survival and function. The use of these markers to identify antibody-mediated rejection is novel and being used to complement existing biomarkers. Additionally, I focused on projects which highlighted the risk factors, clinical course, and innovative treatments for Human Leukocyte Antigen (HLA) and non-HLA antibodies in pediatric kidney transplantation. I have also investigated other factors that can affect kidney transplant outcomes including medication non-adherence, combined organ transplantation and recurrent disease.
- Myers, Nicholas, Dana Droz, Bruce W. Rogers, Hien Tran, Kevin B. Flores, Cliburn Chan, Stuart J. Knechtle, et al. “Modeling BK Virus Infection in Renal Transplant Recipients.” Viruses 17, no. 1 (December 31, 2024). https://doi.org/10.3390/v17010050.
- Kahan, Riley H., Nader Abraham, Hui-Jie Lee, Robert B. Ettenger, Paul C. Grimm, Elaine F. Reed, R Keith Reeves, et al. “Natural Killer Cell Phenotypes and Clinical Outcomes in Pediatric Kidney Transplantation.” Pediatr Transplant 28, no. 8 (December 2024): e14877. https://doi.org/10.1111/petr.14877.
- Wu, Mengxi, Zhiteng Ma, Xianchen Xu, Brandon Lu, Yuyang Gu, Janghoon Yoon, Jianping Xia, et al. “Acoustofluidic-based therapeutic apheresis system.” Nat Commun 15, no. 1 (August 10, 2024): 6854. https://doi.org/10.1038/s41467-024-50053-1.
- Chang, Y. C., and E. T. Chambers. “Infections in Renal Transplantation.” In Feigin and Cherry’s Textbook of Pediatric Infectious Diseases, 9th Edition: 2-Volume Set, 1–2:732-743.e3, 2025. https://doi.org/10.1016/B978-0-323-82763-8.00075-3.
- Shaw, B. I., and E. T. Chambers. “Precision medicine in solid organ transplantation.” In Genomic and Precision Medicine: Infectious and Inflammatory Disease, 401–12, 2019. https://doi.org/10.1016/B978-0-12-801496-7.00020-4.
- Chambers, E. T., and A. D. Kirk. “Antilymphocyte globulin, monoclonal antibodies, and fusion proteins.” In Kidney Transplantation - Principles and Practice, 283–312, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00019-X.
- Kahan, R., Z. Ma, E. David, S. Kaggallu, J. Kwun, S. Knechtle, T. J. Huang, and E. T. Chambers. “Novel Acoustofluidic Apheresis Device for Antibody Removal in a Rodent Model.” In AMERICAN JOURNAL OF TRANSPLANTATION, 23:S1080–81, 2023.
- Pearl, Meghan, Patricia L. Weng, Lucia Chen, Aditi Dokras, Helen Pizzo, Jonathan Garrison, Carrie Butler, et al. “Long term tolerability and clinical outcomes associated with tocilizumab in the treatment of refractory antibody mediated rejection (AMR) in pediatric renal transplant recipients.” In Clin Transplant, 36:e14734, 2022. https://doi.org/10.1111/ctr.14734.
- Pearl, M., L. Chen, P. Weng, E. T. Chambers, and E. F. Reed. “Non-HLA Antibodies to G Protein-Coupled Receptors and Allograft Survival in Pediatric Kidney Transplant Recipients: Short- and Long-Term Outcomes.” In AMERICAN JOURNAL OF TRANSPLANTATION, 22:381–381, 2022.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
- Marlon Chambers- spouse