Duke Health Provider
Our patients are the center of our universe and we look for the best ways possible to treat them.
Adrian F. Hernandez, MD, MHS
Advanced Heart Failure Specialist, Transplant Cardiologist
Duke Health Provider
Call for an Appointment
Areas of Expertise
Heart Failure
Heart Transplant Evaluation
VAD Evaluation Care
Multi-Organ Transplant
Where I See Patients
Duke Cardiology Clinic - Clinic 2F/2G - Durham, NC
Our patients are the center of our universe and we look for the best ways possible to treat them.
Call for an Appointment
My Locations
Closed:
Opening tomorrow at 8:00 am
40 Duke Medicine Cir
Durham,
NC
27710-4000
Fax:
919-681-7177
About Me
I am a cardiologist who specializes in advanced heart failure and heart transplant. I always strive to take a fresh look at patients and see what treatments we can offer that they may have not had before. I spend about half of my time doing clinical research that focuses on the outcomes of patients with heart failure and other cardiovascular diseases. We look for opportunities to improve care and new ways to treat heart disease. Our patients are the center of our universe and we look for the best ways possible to treat them. One of my favorite parts of my job is taking care of patients who think the road has ended and being able to offer them several new roads to improve their lives.
Current Appointments and Affiliations
- Duke Health Cardiology Professor, Medicine, Cardiology 2021
- Professor of Medicine, Medicine, Cardiology 2015
- Vice Dean and Executive Director of Duke Clinical Research, Duke Clinical Research Institute 2020
Languages I Speak
English
Call for an Appointment
Areas of Expertise
Training and Education
Fellowship
Cardiology, Duke University Medical Center, 2000-2004
Residency
Internal Medicine, University of California–San Francisco Medical Center, 1997-2000
Education
MD, University of Texas Southwestern Medical School, 1997
In the News
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For America First, Invest in Science and the NIH
Medscape
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Early Actions by Trump Administration Sow Uncertainty for CV Research
tctMD
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What might the next century hold for cardiovascular disease prevention and care?
American Heart Association
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Everything, Everywhere All at Once: Evidence Generation and Implementation in the Digital Age
Circulation
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Another Trial Finds No Benefit From Ivermectin for COVID Symptoms
U.S. News & World Report
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Study Debunks Use of Antidepressant Luvox as COVID Treatment
U.S. News & World Reports
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COVID debate semi-settled: Antidepressant does not work as treatment
CBS-17
Clinical Focus and Research
Publications and Grants
Grants106
Academic Articles1041
Book Sections3
Conference Papers316
- Increasing the Quality and Efficiency of Clinical Trials (U18) awarded by Food and Drug Administration 2014 - 2029
- Endocrinology and Metabolism Training Program awarded by National Institutes of Health 2024 - 2029
- Pagidipati, Neha, Brooke Heidenfelder, Lydia Coulter Kwee, Fatima Rodriguez, Ranee Chatterjee, Kishan S. Parikh, Michel G. Khouri, et al. “Returning Individual-Level Urgent or Emergent Research Results to Participants: The Project Baseline Health Study Experience.” Am J Med Open 13 (June 2025): 100092. https://doi.org/10.1016/j.ajmo.2025.100092.
- Sandhu, Amneet, Li Qin, Karl Minges, Sarah Zimmerman, Ryan T. Borne, Vincenzo B. Polsinelli, P Michael Ho, et al. “Same-Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States.” J Am Heart Assoc, April 16, 2025, e039190. https://doi.org/10.1161/JAHA.124.039190.
- Ostrominski, John W., Mats C. Højbjerg Lassen, Brian L. Claggett, Zi Michael Miao, Silvio E. Inzucchi, Kieran F. Docherty, Akshay S. Desai, et al. “Sodium-glucose co-transporter 2 inhibitors and new-onset diabetes in cardiovascular or kidney disease.” Eur Heart J 46, no. 14 (April 7, 2025): 1321–31. https://doi.org/10.1093/eurheartj/ehae780.
- Greene, S. J., M. D. Samsky, and A. F. Hernandez. “Leveraging “Big Data” for the Design and Execution of Clinical Trials.” In Principles and Practice of Clinical Trials, 2241–62, 2022. https://doi.org/10.1007/978-3-319-52636-2_161.
- Cotter, G., W. G. Stough, G. M. Felker, E. J. Velazquez, A. F. Hernandez, J. G. Rogers, M. Gheorghiade, K. F. Adams, and C. M. O’Connor. “Acute heart failure: Nomenclature, pathophysiology, and outcome measures.” In Management of Acute Decompensated Heart Failure, 19–38, 2005. https://doi.org/10.4324/9780203421345-7.
- Felker, G. M., A. F. Hernandez, and A. Maisel. “Biologic markers in acute heart failure.” In Management of Acute Decompensated Heart Failure, 151–64, 2005. https://doi.org/10.4324/9780203421345-16.
- Nouhravesh, Nina, Alexander H. Gunn, Derek Cyr, Adrian F. Hernandez, David A. Morrow, Eric J. Velazquez, Jonathan H. Ward, et al. “Sacubitril/valsartan versus valsartan initiation in patients naïve to renin-angiotensin system inhibitors: Insights from PARAGLIDE-HF.” In Eur J Heart Fail, 2025. https://doi.org/10.1002/ejhf.3579.
- Chew, Derek S., Yanhong Li, Robert Bigelow, Patricia A. Cowper, Kevin J. Anstrom, Melanie R. Daniels, Linda Davidson-Ray, et al. “Cost-Effectiveness of Vericiguat in Patients With Heart Failure With Reduced Ejection Fraction: The VICTORIA Randomized Clinical Trial.” In Circulation, 148:1087–98, 2023. https://doi.org/10.1161/CIRCULATIONAHA.122.063602.
- Naggie, Susanna, Aaron Milstone, Mario Castro, Sean P. Collins, Seetha Lakshmi, Deverick J. Anderson, Lizbeth Cahuayme-Zuniga, et al. “Hydroxychloroquine for pre-exposure prophylaxis of COVID-19 in health care workers: a randomized, multicenter, placebo-controlled trial Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine (HERO-HCQ).” In International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, 129:40–48, 2023. https://doi.org/10.1016/j.ijid.2023.01.019.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
This faculty member (or a member of their immediate family) has reported outside activities with the companies or institutions listed below. This information has been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts of interest.
- AstraZeneca
- Boehringer Ingleheim
- Boston Scientific Corporation
- Bristol Myers Squibb
- Eidos Therapeutics
- Intellia
- Intercept
- Merck
- Novartis
- Novo Nordisk
- Prolaio
- TikkunLev Therapeutics, Inc