EA2197 Chemotherapy Before and After Versus After Surgery for Gallbladder Cancer - Clinical Trial

What is the Purpose of this Study?

We are doing this study to compare the usual treatment (surgery plus chemotherapy afterward) to using chemotherapy both before and after surgery.

What is the Condition Being Studied?

Gallbladder Cancer (found after gallbladder was removed during surgery)

Adults 18 years and older who:

Have histologically-confirmed T2 or T3 gallbladder cancer discovered at the time of or following routine cholecystectomy for presumed benign disease
Do not have any evidence of metastatic disease

For more information about who can join this study, contact the study team at 919-668-1861.

Age Group

Adults

This study is divided into 2 groups. If you decide to participate, you will be randomized into 1 of the 2 groups below:

Group 1 (Control Arm - Arm A) receives surgery and then 6 months of chemotherapy (gemcitabine/ cisplatin) after surgery
Group 2 (Treatment Arm - Arm B) receives 3 months of chemotherapy before surgery, followed by 3 months of chemotherapy after surgery