The most common types of amyloidosis are:
- AL amyloidosis. Also known as primary amyloidosis or light chain amyloidosis, AL amyloidosis is caused by abnormal plasma cells in the bone marrow. It can affect the lungs, heart, kidneys, liver, soft tissue, and nervous system.
- ATTR amyloidosis. There are two main types of transthyretin amyloidosis (or ATTR): hereditary and wild-type. ATTR is a common cause of cardiac amyloidosis, when transthyretin proteins accumulate in your heart. ATTR can also cause amyloid neuropathy and damage to other organs and systems.
Symptoms Often Overlooked
Since different organs may be involved, the symptoms of amyloidosis can be overlooked or attributed to other diseases. For example, with cardiac amyloidosis you may experience heart failure and heart rhythm abnormalities like atrial fibrillation. If your nervous system is damaged, you may experience numbness, tingling, or pain. If your kidneys are affected, you may experience foamy urine or kidney failure. Some people have no symptoms at all.