Myeloproliferative Disorders (Neoplasms)

Myeloproliferative disorders, also called myeloproliferative neoplasms, are caused by the overproduction of red blood cells, white blood cells, and/or platelets in the bone marrow. They increase your risk for stroke, blood clots, and heart attack and may cause an enlarged spleen. Common types include:

• Polycythemia vera -- too many red blood cells
• Essential thrombocytosis -- too many platelets, the blood cells that help the blood clot
• Myelofibrosis -- excessive collagen or fibrous tissue in the bone marrow that interferes with blood cell production
• Chronic myelogenous leukemia (CML) -- an increased production of white blood cells in the bone marrow

These diseases have similar criteria for diagnosis, which is why it’s important for one of our experienced specialists to evaluate your condition.

Recognized for Excellence
As a National Cancer Institute-designated Comprehensive Cancer Center, we offer a level of expertise that can only be found in a small number of cancer centers in the country. We are also part of the National Comprehensive Cancer Network (NCCN), an alliance of the nation’s leading cancer centers dedicated to improving patient care.

Extensive Experience
We treat nearly 1,000 people with blood cancers each year. Our experienced doctors are skilled in diagnosing myeloproliferative disorders and developing a treatment plan designed to achieve the best possible outcome.

Quick Genetic Testing Results
Myeloproliferative disorders may be associated with certain genetic mutations. Identifying these genetic irregularities is key to getting an accurate diagnosis. Our specialized molecular diagnostic lab provides prompt genetic testing results -- often within 24 to 48 hours after testing -- so you can begin treatment as soon as possible.

Research Advances
Our doctors investigate new therapies, including targeted agents and stem cell transplants, to treat myeloproliferative disorders. You may benefit from their research before it becomes widely available.

A Team of Specialists
Our blood cancer medical team includes specialists from hematology-oncology, hematopathology, cytogenetics, molecular diagnostics, and adult bone marrow transplant. The team meets regularly to discuss your condition, consider opinions, and offer coordinated and advanced care.

A Caring Environment
You will have access to our comprehensive cancer support services. Support staff can help you understand treatment options and manage the side effects of your treatment. View all of our cancer support groups in our event calendar.

A Whole-Body Approach
Our clinical social worker is available to help you cope with the emotional and psychological stress of your disease, as well as other medical concerns. You may also use our services that incorporate nutrition, guided imagery, anxiety control, and meditation. Our cancer survivorship clinic offers a range of resources to help you after your treatment ends.