Karen Flores Rosario, MD
Advanced Heart Failure Specialist, Transplant Cardiologist
My Locations
About Me
I specialize in advanced heart failure and cardiomyopathy, with a focus on helping patients with heart conditions that run in their families. I understand that living with heart failure can be overwhelming, especially when it's linked to your family's health history. My goal is to provide clear, compassionate care and support, guiding you through every step of managing your condition whether that is understanding your diagnosis, exploring genetic testing options, or the before and after heart transplantation journey. I’m committed to ensuring you feel informed and confident in your care so we can work together to achieve the best possible health outcomes.
LGBTQ+ Identified or Ally
- Assistant Professor of Medicine, Medicine, Cardiology 2024
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Ratings and Reviews
The ratings and reviews are based on patient responses to the overall provider rating question from the survey. The question reads: “Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?” Responses are converted to a 5-point rating system and applied consistently to all providers. Learn more about our survey process. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
Clinical Focus and Research
My research is dedicated to understanding how different genetic heart conditions, like cardiomyopathies, develop and progress over time. I'm passionate about this work because it helps us tailor treatments specifically to each patient's unique heart condition. I’m also interested in how advanced imaging, like cardiac MRI, can give us clearer insights into these heart conditions, allowing us to better understand and manage them.
- Lerman, Joseph B., Veraprapas Kittipibul, Cynthia L. Green, Karen Flores Rosario, Chetan B. Patel, Richa Agarwal, Jeffrey E. Keenan, Carmelo A. Milano, Jacob N. Schroder, and Adam D. DeVore. “Utilization and Outcomes of Ex Vivo Heart Perfusion in Donation After Brain Death Heart Transplantation.” JACC Heart Fail, April 1, 2025. https://doi.org/10.1016/j.jchf.2025.01.027.
- Rosario, Karen Flores, and Melissa A. Daubert. “Improving Diagnosis and Management of Dilated Cardiomyopathy With Advanced Cardiac Imaging and Early Genetic Testing.” JACC Case Rep 29, no. 23 (December 4, 2024): 102824. https://doi.org/10.1016/j.jaccas.2024.102824.
- Flores Rosario, Karen, and Richa Agarwal. “Can Percutaneous Coronary Intervention Change the Score in Cardiac Allograft Vasculopathy?” J Card Fail 30, no. 10 (October 2024): 1231–32. https://doi.org/10.1016/j.cardfail.2024.08.031.
- Snow, Sarah, Karen Flores Rosario, Toi Spates, Jeff Federspiel, Cary Ward, and Andrew Landstrom. “Navigating Pregnancy and Postpartum with a Familial Variant of Unknown Significance: A Complex Clinical Journey,” 2024. https://doi.org/10.1016/S0735-1097(24)06327-7.
- Flores, Karen, Ravi Karra, Albert Y. Sun, and Han W. Kim. “MIMICKING THE GREAT MIMICKER: LMNA CARDIOMYOPATHY PRESENTING AS ISOLATED CARDIAC SARCOIDOSIS.” In Journal of the American College of Cardiology, 81:2501–2501. Elsevier BV, 2023. https://doi.org/10.1016/s0735-1097(23)02945-5.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
- ASK-BIO/ACTUS
- Campbell University Schol of Osteopathic Medicine
- Oliver Wyman Health