Open for Enrollment Soon
This study will open for enrollment soon. Please contact the study team for more information and check back frequently.
TUBA-WISP II Trial (Ovarian Cancer) - Clinical Trial
What is the Purpose of this Study?
We are doing this study to compare 2 different surgical options for the prevention of ovarian cancer. We want to know which option is likely to produce the best outcomes for women who have genetic mutations that put them at high risk for developing ovarian cancer.
What is the Condition Being Studied?
Ovarian Cancer Prevention
Who Can Participate in the Study?
Women who:
- Are ages 25-40 and positive for BRCA1 mutation; OR
- Are ages 25-45 and positive for BRCA2 mutation; OR
- Are ages 30-50 and positive for BRIP1, RAD51C, RAD51D, and PALB2 mutations
For more information, contact the study team at lauren.march@duke.edu.
Age Group
Adults
What is Involved?
If you choose to join this study, you will discuss 2 different options for prevention of ovarian cancer with the study doctor and team and make your choice of which option you would like to pursue. The 2 options are:
- Risk-Reducing Salpingectomy with Delayed Risk-Reducing Oophorectomy: This option involves removing one or both fallopian tubes and then having one or both ovaries removed at a later time. This option is not the standard-of-care at this time.
- Risk-Reducing Salpingo-oopherectomy: This option involves the removal of one or both fallopian tubes and one or both ovaries at the same time. It is considered the standard-of-care option at this time.
Study Details
Full Title
RISK REDUCING SALPINGECTOMY WITH DELAYED OOPHORECTOMY AS AN
ALTERNATIVE TO RISK- REDUCING SALPINGO-OOPHORECTOMY IN HIGH RISKWOMEN TO ASSESS THE SAFETY OF PREVENTION ? US COHORT STUDY
Principal Investigator
Gynecologic Oncologist
Protocol Number
IRB:
PRO00116596
Phase
Phase
N/A
Enrollment Status
Open for Enrollment Soon