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We are delighted to welcome the former Lake Norman Regional Medical Center (LNRMC) in Mooresville, NC into the Duke Health family as Duke Health Lake Norman Hospital!

Open for Enrollment Soon
This study will open for enrollment soon. Please contact the study team for more information and check back frequently.

Repeatability of Magnetic Resonance Imaging in Patients with IDH1 Mutant Glioma on Ivosidenib - Clinical Trial

What is the Purpose of this Study?

We are doing this study to create a database of MRI images taken from patients with low-grade diffuse glioma who are being treated with ivosidenib. We want to use these images for analysis that might help us make better predictions about how we can expect tumors to grow for people diagnosed with low-grade diffuse glioma.

What is the Condition Being Studied?

Low-Grade Diffuse Glioma

Who Can Participate in the Study?

Adults ages 18-70 who:

  • Are diagnosed with IDH1 mutant low-grade glioma (WHO grade 2)
  • Are currently taking ivosidenib
  • Are able to have MRI scans

For more information, contact the study team at 919-684-5301.

Age Group
Adults

What is Involved?

If you choose to join this study, you will have an MRI scan that is part of your clinical care. This will include a routine MRI scan with intravenous contrast agent using the Brain Tumor Imaging Protocol (BTIP). There will be additional research imaging sequences before this routine clinical care scan that will add about 15 minutes to the standard imaging time of 30 minutes to 1 hour.

You will take part in this study for only the one day during which you are scheduled to receive your MRI scan.

Study Details

Full Title
Repeatability of Magnetic Resonance Imaging in Patients with IDH1 Mutant Glioma on Ivosidenib.
Principal Investigator
Protocol Number
IRB: PRO00116521
NCT: NCT06648473
Phase
Phase N/A
ClinicalTrials.gov
Enrollment Status
Open for Enrollment Soon