MOAB Trial: Optimal Atezolizumab for rGBM (Recurrent Glioblastoma) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if giving patients a drug called atezolizumab before and after surgery for recurrent glioblastoma can improve how their cancer responds.

What is the Condition Being Studied?

Recurrent Glioblastoma

Who Can Participate in the Study?

Adults ages 18+ who:

  • Are diagnosed with glioblastoma (isocitrate dehydrogenase wildtype)
  • Have a recurrence after treatment with radiation and temozolomide
  • Plan to have surgery

For more information about who can join this study, please contact the study team at 919-684-5301.

Age Group
Adults

What is Involved?

If you join the study, you will:

  • Have a physical exam and other tests
  • Have magnetic resonance imaging (MRI) scans of the brain
  • Have blood draws
  • Get atezolizumab before surgery
  • Get atezolizumab after surgery

Study Details

Full Title
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
Principal Investigator
Protocol Number
IRB: PRO00113395
NCT: NCT06069726
Phase
Phase N/A
ClinicalTrials.gov
Enrollment Status
Open for Enrollment
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