Survivorship Post-HCT Optimization Program (S-POP) - Clinical Trial

Email to Participate

What is the Purpose of this Study?

We are doing this study to evaluate whether exercise training following allogeneic stem cell transplant can improve physical function, cognitive function, mental health, social support, and quality of life.

What is the Condition Being Studied?

Allogeneic (Donor) Stem Cell Transplant

Who Can Participate in the Study?

Adults aged 18-80 who:

Are 60-120 days post-allogeneic stem cell transplant at Duke
Are able to safely take part in an exercise program (you will do CPET testing to be cleared to participate)

The caregivers of these patients may also participate.

For more information about who can join this study, please contact the study team at lauren.hill@duke.edu or 919-668-2369.

What is Involved?

If you choose to join the study, you will:

Be assigned to an exercise program that consists of three 30-minute high-intensity interval training (HIIT) sessions and two resistance training sessions per week for 12 weeks.
Use an Apple Watch and iPhone to track your activity and complete daily entries in an app
Fill out questionnaires
Do assessments to measure your physical function
Have Cardiopulmonary Exercise Testing (CPET) done
Have complete body composition testing done
Have your muscles scanned with a handheld ultrasound device
Give stool samples
Have your skin swabbed
Have blood draws
Monitor your vital signs at home with a scale and blood pressure cuff

If your caregiver chooses to join the study, they will:

Be assigned to an exercise program that consists of three 30-minute high-intensity interval training (HIIT) sessions and two resistance training sessions per week for 12 weeks
Fill out questionnaires
Do assessments to measure their physical function
Have Cardiopulmonary Exercise Testing (CPET) done
Give stool samples
Have their skin swabbed

Study Details

Full Title

The effect of high-intensity interval training (HIIT) and resistance training on function, health, and quality of life outcomes following hematopoietic stem cell transplant

Principal Investigator

Chenyu Lin, MD

Hematologic Oncologist

Protocol Number

IRB: PRO00110028

NCT: NCT05238376

ClinicalTrials.gov

View on ClinicalTrials.gov

Enrollment Status

Open for Enrollment

Participate

Email lauren.bohannon@duke.edu

Contact the Duke Recruitment Innovation Center

MyResearchPartners@duke.edu

919-681-5698