Brian E. Brigman, MD, PhD
Orthopaedic Surgical Oncologist
My Locations
Part of the Duke Cancer Institute
About Me
As an orthopaedic oncologist, I am passionate about providing the best diagnostic and therapeutic surgical care for patients with benign or malignant bone or soft tissue tumors of the musculoskeletal system. As the director of the Sarcoma program at the Duke Cancer Institute, my passion is building our team to provide the best clinical care and basic scientific, translational and clinical research to serve our patients.
- Professor of Orthopaedic Surgery, Orthopaedic Surgery 2020
- Professor in Pediatrics, Pediatrics 2020
- Member of the Duke Cancer Institute, Duke Cancer Institute 2012
Ratings and Reviews
The ratings and reviews are based on patient responses to the overall provider rating question from the survey. The question reads: “Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?” Responses are converted to a 5-point rating system and applied consistently to all providers. Learn more about our survey process. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
Clinical Focus and Research
- Fresh Tissue Lab Agreement awarded by DePuy Synthes Companies 2019 - 2019
- Protocol Number: 14-03-PATHOLHUM-02 awarded by IlluminOss Medical, Inc. 2015 - 2018
- Biermann, J Sybil, Angela Hirbe, Shivani Ahlawat, Nicholas M. Bernthal, Odion Binitie, Sarah Boles, Brian Brigman, et al. “Bone Cancer, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.” J Natl Compr Canc Netw 23, no. 4 (April 2025). https://doi.org/10.6004/jnccn.2025.0017.
- Devinney, Michael J., Andrew R. Spector, Mary C. Wright, Jake Thomas, Pallavi Avasarala, Eugene Moretti, Jennifer E. Dominguez, et al. “The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.” Anesth Analg 140, no. 1 (January 1, 2025): 99–109. https://doi.org/10.1213/ANE.0000000000007269.
- Ferlauto, Harrison R., Bruno Belanger, Alexander L. Lazarides, Julia D. Visgauss, Brian E. Brigman, and William C. Eward. “Locking plate augmentation of polymethylmethacrylate-filled distal femoral defects: A biomechanical study.” J Orthop Res 43, no. 1 (January 2025): 210–16. https://doi.org/10.1002/jor.25965.
- Mowery, Yvonne Marie, Karla V. Ballman, Angela M. Hong, Scott Schuetze, Andrew J. Wagner, Varun Monga, Rachel Heise, et al. “SU2C-SARC032: A randomized trial of neoadjuvant RT and surgery with or without pembrolizumab for soft tissue sarcoma.” In JOURNAL OF CLINICAL ONCOLOGY, Vol. 42, 2024.
- Catanzano, A. A., S. P. Ryan, A. L. Lazarides, B. E. Brigman, and W. C. Eward. “New Techniques for Diagnosis and Treatment of Musculoskeletal Tumors: Methods of Intraoperative Margin Detection.” In Techniques in Orthopaedics, 33:148–57, 2018. https://doi.org/10.1097/BTO.0000000000000290.
- Mowery, Yvonne Marie, Karla V. Ballman, Richard F. Riedel, Brian E. Brigman, Steven Attia, Christian Frederick Meyer, Scott Schuetze, et al. “SU2C-SARC032: A phase II randomized controlled trial of neoadjuvant pembrolizumab with radiotherapy and adjuvant pembrolizumab for high-risk soft tissue sarcoma.” In Journal of Clinical Oncology, 36:TPS11588–TPS11588. American Society of Clinical Oncology (ASCO), 2018. https://doi.org/10.1200/jco.2018.36.15_suppl.tps11588.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- Healthy Blue
- NC Medicaid Direct
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
- Deciphera
- Musculoskeletal Transplant Foundation